Kartal Koşuyolu Araştırma Yüksek İhtisas Eğitim ve Hastanesi

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1 Kartal Koşuyolu Araştırma Yüksek İhtisas Eğitim ve Hastanesi
PERKÜTAN MİTRAL KAPAK TAMİRİ Endikasyonlar ve Klinik Çalışmalar kapak tamir atölyesi 1-2 Kasım 2013, İSTANBUL Dr. Selçuk Pala Kartal Koşuyolu Araştırma Yüksek İhtisas Eğitim ve Hastanesi

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3 European Heart Journal (2007) 28, 1358–1365

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5 EVEREST I (Endovascular Valve Edge-to-Edge Repair)
inclusion criteria All patients were potential candidates for MV surgery symptomatic and/or had compromised LV function(LVEF <60% or LVESD >45 mm). With regard to MR severity, patients met at least three out of six criteria for severity, one of which was quantitative.

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7 EVEREST I exclusion criteria
Etiology of MR being infectious or rheumatic LVEF of <30% LVES dimension of >55 mm MV area of <4.0 cm2

8 EVEREST I

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17 EVEREST II

18 EVEREST II

19 EVEREST II

20 EVEREST II

21 EVEREST II

22 EVEREST II

23 EVEREST II

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25 EVEREST II

26 EVEREST II

27 EVEREST II

28 EVEREST II

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32 EVEREST II HRR

33 EVEREST II comparator group (n= 36)

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35 EVEREST HRS

36 EVEREST II HRS

37 EVEREST HRS

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40 ACCESS EU

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45 ACCESS EU

46 ACCESS EU

47 ACCESS EU

48 ESC

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50 SUMMARY The MitraClip procedure can be performed safely with low major advers event rate. Beyond 6 months, the rate of MV surgery low in the MitraClip patients

51 SUMARY SURGERY İS the standard of care for treatment of MR among elegible patient

52 SUMMARY Clinical benefits provided by MitraClip is durable through 4 years ** Reduced in MR severity ** İmprovment in LV Dimension ** İmprovments in NYHA Functional Class

53 Conclusion The MitraClip procedure is a therapeutic option for selected patients with significant MR

54 Kartal Koşuyolu Araştırma Yüksek İhtisas Eğitim ve Hastanesi
PERKÜTAN MİTRAL KAPAK TAMİRİ Endikasyonlar ve Klinik Çalışmalar kapak tamir atölyesi 1-2 Kasım 2013, İSTANBUL Dr. Selçuk Pala Kartal Koşuyolu Araştırma Yüksek İhtisas Eğitim ve Hastanesi